Slu7 Gene Summary [Rat]
Predicted to enable pre-mRNA 3'-splice site binding activity; second spliceosomal transesterification activity; and zinc ion binding activity. Predicted to be involved in cellular response to heat; intracellular protein transport; and mRNA splicing, via spliceosome. Predicted to be located in cytosol and nuclear speck. Predicted to be part of catalytic step 2 spliceosome and small nuclear ribonucleoprotein complex. Orthologous to human SLU7 (SLU7 homolog, splicing factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slu7 |
| Official Name | SLU7 homolog, splicing factor [Source:RGD Symbol;Acc:631432] |
| Ensembl ID | ENSRNOG00000003822 |
| Bio databases IDs | |
| Aliases | SLU7 homolog, splicing factor |
| Synonyms | 9G8, D11Ertd730e, D3Bwg0878e, hSlu7, SLU7 homolog, splicing factor, SLU7 splicing factor homolog (S. cerevisiae) |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slu7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- pre-mRNA 3' splice site binding
- Pre-mRNA splicing Prp18-interacting factor
- enzyme
- protein binding
- second spliceosomal transesterification
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- systemic lupus erythematosus
- infection by HIV-1
role in cell
- expression in
- apoptosis
- production in
- cell viability
- response by
- alternative splicing by
- autophagy by
- alternative splicing in
- reverse transcription in
- reverse transcription
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- catalytic step 2 spliceosome
- Cytoplasm
- cytosol
- spliceosomes
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slu7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing, via transesterification reactions
- RNA splicing
- cellular response to heat
- alternative nuclear mRNA splicing, via spliceosome
- intracellular protein transport
- nuclear mRNA 3'-splice site recognition
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- catalytic step 2 spliceosome
- cytoplasm
- nuclear speck
- intracellular membrane-bounded organelle
- membrane
- cytosol
- spliceosomal complex
- small nuclear ribonucleoprotein complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- second spliceosomal transesterification activity
- zinc ion binding
- protein binding
- pre-mRNA 3'-splice site binding