Zc3h11a Gene Summary [Rat]

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Predicted to be involved in negative regulation of muscle cell differentiation; regulation of DNA-templated transcription; and regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to act upstream of or within blastocyst hatching and negative regulation of transcription by RNA polymerase II. Predicted to be located in centriolar satellite; cytoplasm; and nuclear lumen. Predicted to be active in nucleus. Orthologous to human ZBED6 (zinc finger BED-type containing 6). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zc3h11a
Official Name
zinc finger CCCH-type containing 11A [Source:RGD Symbol;Acc:1308290]
Ensembl ID
ENSRNOG00000053210
Bio databases IDs NCBI: 360845 Ensembl: ENSRNOG00000053210
Aliases zinc finger CCCH-type containing 11A
Synonyms 1110003F06Rik, 5730454B08RIK, G630041M05Rik, KIAA0663, mKIAA0663, RGD1308290, ZC3HDC11A, Zc3hh11a, zinc finger CCCH-type containing 11A
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zc3h11a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • zinc finger
  • Zinc-finger containing family
  • RNA-binding, Nab2-type zinc finger
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • male pattern hair loss
  • coronary artery disease
  • alopecia
regulated by
role in cell
  • replication in
  • JQ1 resistance
  • binding in
  • autophagy in
  • polyadenylation in
  • autophagy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zc3h11a gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • poly(A)+ mRNA export from nucleus

Cellular Component

Where in the cell the gene product is active
  • transcription export complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.