Serpina3m Gene Summary [Rat]
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in response to cytokine. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; cystic fibrosis; and vasculitis. Orthologous to human SERPINA3 (serpin family A member 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Serpina3m |
| Official Name | serine (or cysteine) proteinase inhibitor, clade A, member 3M [Source:RGD Symbol;Acc:735068] |
| Ensembl ID | ENSRNOG00000009921 |
| Bio databases IDs | |
| Aliases | serine (or cysteine) proteinase inhibitor, clade A, member 3M |
| Synonyms | Contrapsin like protease inhibitor 1, CPi-21, GHR-P63, Kallistatin1, Kallistatin2, Kallistatin3, Kallistatin4, Kallistatin5, Kbp, Klkbp, serine (or cysteine) proteinase inhibitor, clade A, member 3C, Serine protease inhibitor 2b, Serpina3, Serpina3c, Serpina3k, Serpina3m, serpin family A member 3M, SPI-2, SPI-2.3, SPI-2.4, Spin2, Spin2b, Thyroid hormone regulated protease inhibitor |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Serpina3m often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SERine Proteinase INhibitors (serpin) family
- Serpin (serine protease inhibitor)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- soluble fraction
- plasma