Abhd2

Predicted to enable several functions, including acetylesterase activity; lipase activity; and nuclear steroid receptor activity. Predicted to be involved in several processes, including medium-chain fatty acid metabolic process; response to progesterone; and sperm capacitation. Predicted to act upstream of or within negative regulation of smooth muscle cell migration and response to wounding. Predicted to be located in acrosomal vesicle. Predicted to be active in sperm flagellum and sperm plasma membrane. Orthologous to human ABHD2 (abhydrolase domain containing 2, acylglycerol lipase). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Abhd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Abhd2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Abhd2 gene, providing context for its role in the cell.