Adgra1 Gene Summary [Rat]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in glutamatergic synapse; plasma membrane; and postsynaptic density. Orthologous to human ADGRA1 (adhesion G protein-coupled receptor A1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Adgra1
Official Name
adhesion G protein-coupled receptor A1 [Source:NCBI gene;Acc:309097]
Ensembl ID
ENSRNOG00000054955
Bio databases IDs NCBI: 309097 Ensembl: ENSRNOG00000054955
Aliases adhesion G protein-coupled receptor A1
Synonyms 2900059M17Rik, adhesion G protein-coupled receptor A1, D7ERTD680E, GPR123
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Adgra1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane receptor (Secretin family)
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Adgra1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • insomnia
  • gastroesophageal reflux
regulated by
  • TGFB1
  • IFNG
  • E. coli serotype 0127B8 lipopolysaccharide
  • CREB1
  • A-CREB
  • forskolin
regulates
  • oxygen
  • carbon dioxide
role in cell
  • size

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • glutaminergic synapse
  • cellular membrane
  • postsynaptic density

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Adgra1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • signal transduction
  • cell surface receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • postsynaptic density
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.