Adgra1 Gene Summary [Mouse]
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including adrenal gland; brain; eye; genitourinary system; and spinal cord. Orthologous to human ADGRA1 (adhesion G protein-coupled receptor A1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adgra1 |
| Official Name | adhesion G protein-coupled receptor A1 [Source:MGI Symbol;Acc:MGI:1277167] |
| Ensembl ID | ENSMUSG00000025475 |
| Bio databases IDs | |
| Aliases | adhesion G protein-coupled receptor A1 |
| Synonyms | 2900059M17Rik, adhesion G protein-coupled receptor A1, D7ERTD680E, GPR123 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adgra1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- 7 transmembrane receptor (Secretin family)
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Adgra1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cellular membrane
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Adgra1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- signal transduction
- cell surface receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- postsynaptic density
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity