QIAseq Targeted DNA Pro Panels

For unprecedented ease-of-use and biological insights using targeted DNA sequencing

  • Less than 6 hours total turnaround time to go from setup to sequencing
  • Flexibility to multiplex QIAseq Targeted DNA Pro libraries with other chemistries
  • New enzymatic process for preventing adapter and primer carryover contamination, eliminating time-consuming bead purifications
  • Reveal structural variants with breakpoints defined at the nucleotide level that span multiple exons, in addition to SNPs and indels

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Panel Development

Learn how we develop our NGS panels, focusing on selecting clinically relevant genes and variants based on solid medical guidelines and research. Below are the details on the careful process behind these tools, ensuring they offer accurate and efficient genomic analysis for research purposes.
Somatic Variant Detection - Focus

The QIAseq Targeted DNA Pro Focus Panels enable a Sample to Insight workflow for a targeted next generation sequencing analysis of actionable and interpretable cancer-related somatic variants in oncogenes and tumor suppressor genes relevant for tumor classification.

We specifically collect targeted actionable and interpretable genes and variants from

  1. clinical practice guidelines recommended by multiple organizations, including the American College of Medical Genetics (ACMG), the American Society Of Hematology (ASH), the Association for Molecular Pathology (AMP), the American Society of Clinical Oncology (ASCO), the College of American Pathologists (CAP), the European Society for Medical Oncology (ESMO), and the National Comprehensive Cancer Network (NCCN);
  2. the NIH NCBI ClinVar and Online Mendelian Inheritance in Man (OMIM) resources that compile variants with known associations to cancers cited by peer-reviewed publications,
  3. clinical trial documents from resources such as Cancer.gov, ClinicalTrials.gov, and the UMIN Clinical Trials Registry;
  4. requests and suggestions from QIAGEN KOLs and SMEs; and
  5. other peer-reviewed publications.
As a result, QIAseq Targeted DNA Pro panels give researchers a comprehensive insight into cancer genomics.

 

Building on our expertise to employ unique molecular indices (UMIs) to correct for PCR amplification bias and to use single primer extension (QIAseq enrichment technology) technology for highly-specific target enrichment, QIAseq Targeted DNA Pro Panels offer a streamlined library preparation workflow that takes less than 6 hours with minimum hands-on time.

The simplicity of QIAseq Targeted DNA Pro Focus Panels is ideal for routine known cancer mutation detection and screening in any research laboratory with access to next-generation sequencing (NGS) platforms from Illumina and Ion Torrent.

Somatic Variant Detection - Research

The QIAseq Targeted DNA Pro Research Panels enable a Sample to Insight workflow for a targeted next generation sequencing analysis of the entire coding region of relevant oncogenes and tumor suppressor genes. The panels also target actionable and interpretable cancer-related somatic variants relevant for tumor classification.

We specifically collect targeted actionable and interpretable genes and variants from

  1. clinical practice guidelines recommended by multiple organizations, including the American College of Medical Genetics (ACMG), the American Society Of Hematology (ASH), the Association for Molecular Pathology (AMP), the American Society of Clinical Oncology (ASCO), the College of American Pathologists (CAP), the European Society for Medical Oncology (ESMO), and the National Comprehensive Cancer Network (NCCN);
  2. the NIH NCBI ClinVar and Online Mendelian Inheritance in Man (OMIM) resources that compile variants with known associations to cancers cited by peer-reviewed publications,
  3. clinical trial documents from resources such as Cancer.gov, ClinicalTrials.gov, and the UMIN Clinical Trials Registry;
  4. requests and suggestions from QIAGEN KOLs and SMEs; and
  5. other peer-reviewed publications.
As a result, QIAseq Targeted DNA Pro panels give researchers a comprehensive insight into cancer genomics.

 

Building on our expertise to employ unique molecular indices (UMIs) to correct for PCR amplification bias and to use single primer extension (QIAseq enrichment technology) technology for highly-specific target enrichment, QIAseq Targeted DNA Pro Panels offer a streamlined library preparation workflow that takes less than 6 hours with minimum hands-on time.

The simplicity of QIAseq Targeted DNA Pro Research Panels is ideal for routine known and novel cancer mutation detection and screening in any research laboratory with access to next-generation sequencing (NGS) platforms from Illumina and Ion Torrent.

Germline variant detection

The QIAseq Targeted DNA Pro Hereditary Cancer Panels enable a Sample to Insight workflow for a targeted next generation sequencing analysis of the entire coding region of relevant oncogenes and tumor suppressor genes. The panels also target actionable and interpretable cancer-related germline variants relevant for tumor classification.

We specifically collect targeted actionable and interpretable genes and variants from

  1. clinical practice guidelines recommended by multiple organizations, including the American College of Medical Genetics (ACMG);
  2. the NIH NCBI ClinVar and Online Mendelian Inheritance in Man (OMIM) resources that compile variants with known associations to cancers cited by peer-reviewed publications,
  3. the St. Jude Children's Research Hospital’s Pediatric Cancer Genome Project list of discovered driver mutations;
  4. requests and suggestions from QIAGEN KOLs and SMEs; and
  5. other peer-reviewed publications.
As a result, QIAseq Targeted DNA Pro panels give researchers a comprehensive insight into cancer genomics.

 

Building on our expertise to employ unique molecular indices (UMIs) to correct for PCR amplification bias and to use single primer extension (QIAseq enrichment technology) technology for highly-specific target enrichment, QIAseq Targeted DNA Pro Panels offer a streamlined library preparation workflow that takes less than 6 hours with minimum hands-on time.

The simplicity of QIAseq Targeted DNA Pro Hereditary Cancer Panels is ideal for routine known and novel cancer mutation detection and screening in any research laboratory with access to next-generation sequencing (NGS) platforms from Illumina and Ion Torrent.

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Time-efficent NGS workflow for oncology biomarker analyses

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Do you want to create a custom panel or to boost an existing one?

 

Unlock the full potential of your genomic research with QIAseq Targeted DNA Pro Panels. Our cutting-edge solution offers unparalleled precision in DNA sequencing, enabling researchers to delve into genetic insights with unmatched accuracy and efficiency. Whether you're targeting specific genes or exploring complex genetic landscapes, our panels provide a robust foundation for your discoveries. Dive deeper into your research with QIAseq and unveil the secrets of the genome with confidence and clarity.