Oas1c Gene Summary [Mouse]

Enables double-stranded RNA binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of cytokine production; and regulation of innate immune response. Predicted to be located in mitochondrion and ribosome. Predicted to be active in cytosol; membrane; and nucleoplasm. Predicted to colocalize with cytoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 100. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Oas1c
Official Name
2'-5' oligoadenylate synthetase 1C [Source:MGI Symbol;Acc:MGI:2149633]
Ensembl ID
ENSMUSG00000001166
Bio databases IDs NCBI: 114643 Ensembl: ENSMUSG00000001166
Aliases 2'-5' oligoadenylate synthetase 1C
Synonyms 2'-5' oligoadenylate synthetase 1C, 2'-5' oligoadenylate synthetase 1D, 2'-5' oligoadenylate synthetase 1E, Oas1d, Oas1e, Oasl2, Oasl5, oasl7, oasl8
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Oas1c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
  • double-stranded RNA binding
  • enzyme inhibitor activity
  • enzyme
  • protein binding
  • 2'-5'-oligoadenylate synthetase

Pathways

Biological processes and signaling networks where the Oas1c gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • diabetic nephropathy
regulated by
  • Listeria monocytogenes 10403S
  • CpG oligonucleotide
  • FIGLA
  • Yersinia pestis
  • poly rI:rC-RNA
  • Mef cells
  • DUSP11
  • SP600125
  • IFN beta
  • cigarette smoke

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Nucleus
  • Mitochondria
  • cytosol
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.