Dusp11 Gene Summary [Mouse]
Predicted to enable RNA binding activity; polynucleotide 5'-phosphatase activity; and protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in fibrillar center; intercellular bridge; and nuclear speck. Is expressed in central nervous system and retina. Orthologous to human DUSP11 (dual specificity phosphatase 11). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dusp11 |
| Official Name | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) [Source:MGI Symbol;Acc:MGI:1919352] |
| Ensembl ID | ENSMUSG00000030002 |
| Bio databases IDs | |
| Aliases | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
| Synonyms | 2010300F21Rik, dual specificity phosphatase 11, dual specificity phosphatase 11 (RNA/RNP complex 1-interacting), LOC100911499, LOC103690006, PIR1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dusp11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dual specificity phosphatase, catalytic domain
- Protein tyrosine phosphatase, catalytic domain, undefined specificity
- protein-tyrosine-phoshatase
- phosphoprotein phosphatase
- phosphatase
- polynucleotide 5'-phosphatase
- PTP_DSP_cys
- Protein tyrosine phosphatase, catalytic domain motif
- RNA binding
Pathways
Biological processes and signaling networks where the Dusp11 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic lymphocytic leukemia
- endotoxin shock response
role in cell
- production in
- phosphorylation in
- replication in
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- fibrillar center
- Mitochondria
- cytoplasmic bridges
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dusp11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein dephosphorylation
- RNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- intercellular bridge
- nuclear speck
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein tyrosine phosphatase activity
- phosphatase activity
- polynucleotide 5'-phosphatase activity