Hsdl2 Gene Summary [Mouse]
Predicted to enable oxidoreductase activity. Involved in cholesterol homeostasis. Located in mitochondrion. Orthologous to human HSDL2 (hydroxysteroid dehydrogenase like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hsdl2 |
| Official Name | hydroxysteroid dehydrogenase like 2 [Source:MGI Symbol;Acc:MGI:1919729] |
| Ensembl ID | ENSMUSG00000028383 |
| Bio databases IDs | |
| Aliases | hydroxysteroid dehydrogenase like 2 |
| Synonyms | 2610207I16Rik, C9orf99, hydroxysteroid dehydrogenase like 2, RGD1305387, SDR13C1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hsdl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- SDR family mycofactocin-dependent oxidoreductase
- SCP-2 sterol transfer family
- pteridine reductase
- enzyme
- short chain dehydrogenase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hsdl2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- peroxisome
- mitochondrion
- membrane
Molecular Function
What the gene product does at the molecular level
- steroid dehydrogenase activity