ACSM2B Gene Summary [Human]
Enables benzoate-CoA ligase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ACSM2B |
| Official Name | acyl-CoA synthetase medium chain family member 2B [Source:HGNC Symbol;Acc:HGNC:30931] |
| Ensembl ID | ENSG00000066813 |
| Bio databases IDs | |
| Aliases | acyl-CoA synthetase medium chain family member 2B, xenobiotic/medium chain fatty acid:CoA ligase |
| Synonyms | ACSM2, Acsm2a, acyl-CoA synthetase medium-chain family member 2, acyl-CoA synthetase medium chain family member 2B, HXMA, HYST1046, KS, LOC348158, RGD: 708383 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ACSM2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- fatty-acid ligase
- AMP-binding enzyme
- benzoate-CoA ligase family
- CoA-ligase
- Adenylate forming domain, Class I superfamily
- enzyme
- protein binding
- benzoate-CoA ligase
- amino acid adenylation domain
- AMP-binding enzyme C-terminal domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ACSM2B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acyl-CoA metabolic process
- xenobiotic metabolic process
- fatty acid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- medium-chain fatty acid-CoA ligase activity
- ATP binding
- CoA-ligase activity
- protein binding
- benzoate-CoA ligase activity
- metal ion binding
- fatty-acyl-CoA synthase activity
- fatty acid ligase activity