TECTA Gene Summary [Human]
Predicted to enable alpha-tubulin binding activity. Predicted to be involved in microtubule cytoskeleton organization; post-chaperonin tubulin folding pathway; and tubulin complex assembly. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TECTA |
| Official Name | tectorin alpha [Source:HGNC Symbol;Acc:HGNC:11720] |
| Ensembl ID | ENSG00000109927 |
| Bio databases IDs | |
| Aliases | tectorin alpha |
| Synonyms | AP000646.1, TBCEL-TECTA readthrough |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TECTA often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nidogen-like
- Trypsin Inhibitor like cysteine rich domain
- von Willebrand factor type C domain
- protein phosphatase 1 regulatory subunit 42
- Zona pellucida (ZP) domain
- Zona pellucida-like domain
- trypsin inhibitor-like cysteine rich domain
- von Willebrand factor type D domain
- Leucine rich repeat
- von Willebrand factor (vWF) type D domain
- C8 domain
- Coagulation Factor Xa inhibitory site
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hereditary disorder
- autosomal recessive deafness type 21
- autosomal dominant deafness 12
- autosomal recessive deafness
- systemic lupus erythematosus
- familial nonsyndromic hearing impairment
- ear malformation
- Ménière disease
- sensorineural hearing loss
- hearing loss
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown