GNMT Gene Summary [Human]
This locus represents naturally occurring readthrough transcription between the upstream CNPY3 (canopy FGF signaling regulator 3) and the downstream GNMT (glycine N-methyltransferase) genes. Readthrough transcripts may encode proteins that have amino acid similarity with proteins encoded by both individual genes. [provided by RefSeq, Jan 2016]
Details
| Type | Protein Coding |
| Official Symbol | GNMT |
| Official Name | glycine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:4415] |
| Ensembl ID | ENSG00000124713 |
| Bio databases IDs | |
| Aliases | glycine N-methyltransferase |
| Synonyms | CNPY3-GNMT readthrough |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GNMT often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- AdoMet_MTases
- methyltransferase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- glycine N-methyltransferase deficiency
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown