TBC1D7 Gene Summary [Human]
This locus represents naturally occurring readthrough transcription between the neighboring TBC1D7 (TBC1 domain family member 7) gene and downstream uncharacterized LOC100130357 on chromosome 6. Readthrough transcripts may encode the same protein as TBC1 domain family member 7 or may be candidates for nonsense-mediated mRNA decay (NMD). [provided by RefSeq, Jan 2016]
Details
| Type | Protein Coding |
| Official Symbol | TBC1D7 |
| Official Name | TBC1 domain family member 7 [Source:HGNC Symbol;Acc:HGNC:21066] |
| Ensembl ID | ENSG00000145979 |
| Bio databases IDs | |
| Aliases | TBC1 domain family member 7, TS complex subunit 3 |
| Synonyms | TBC1D7-LOC100130357 readthrough |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TBC1D7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme binding
- GTPase activator
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
- MTORC1
- GTPase
role in cell
- response
- assembly
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- basal bodies
- cytosol
- lysosome membrane
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TBC1D7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to growth factor stimulus
- positive regulation of protein ubiquitination
- cellular response to starvation
- negative regulation of TOR signaling cascade
- positive regulation of GTPase activity
Cellular Component
Where in the cell the gene product is active
- cilium basal body
- cytoplasmic vesicle
- cytosol
- TSC1-TSC2 complex
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase activator activity
- small GTPase binding