BIRC8 Gene Summary [Human]
Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; positive regulation of canonical Wnt signaling pathway; and positive regulation of protein ubiquitination. Predicted to be active in cytoplasm; nucleus; and spindle microtubule. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | BIRC8 |
| Official Name | baculoviral IAP repeat containing 8 [Source:HGNC Symbol;Acc:HGNC:14878] |
| Ensembl ID | ENSG00000163098 |
| Bio databases IDs | |
| Aliases | baculoviral IAP repeat containing 8, IAP-like protein 2, inhibitor of apoptosis-like protein 2 |
| Synonyms | baculoviral IAP repeat containing 8, hILP2, IAP-like protein 2, ILP-2, RNF136, TS-IAP |
| Species | Human, Homo sapiens |
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human BIRC8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of apoptotic process
- apoptotic process
- positive regulation of canonical Wnt receptor signaling pathway
- positive regulation of protein ubiquitination
- regulation of cell cycle
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process