TMEM37 Gene Summary [Human]

Predicted to enable calcium channel activity and voltage-gated ion channel activity. Predicted to be involved in calcium ion transmembrane transport and regulation of ion transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TMEM37
Official Name
transmembrane protein 37 [Source:HGNC Symbol;Acc:HGNC:18216]
Ensembl ID
ENSG00000171227
Bio databases IDs NCBI: 140738 Ensembl: ENSG00000171227
Aliases transmembrane protein 37
Synonyms PR, PR1, transmembrane protein 37
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM37 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Voltage-dependent calcium channel gamma-like subunit protein family
  • ion channel

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMEM37 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • calcium ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • ion channel complex

Molecular Function

What the gene product does at the molecular level
  • calcium channel activity
  • voltage-gated ion channel activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.