PFN4 Gene Summary [Human]

Predicted to enable actin monomer binding activity. Predicted to be involved in sequestering of actin monomers. Predicted to be located in cytoskeleton. Predicted to be active in cell cortex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PFN4
Official Name
profilin family member 4 [Source:HGNC Symbol;Acc:HGNC:31103]
Ensembl ID
ENSG00000176732
Bio databases IDs NCBI: 375189 Ensembl: ENSG00000176732
Aliases profilin family member 4
Synonyms 2900024P18Rik, profilin family member 4, profilin family, member 4
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PFN4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PROF
  • Profilin

Pathways

Biological processes and signaling networks where the PFN4 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
  • assembly
  • motility

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PFN4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • acrosome assembly
  • sequestering of actin monomers
  • sperm motility
  • spermatogenesis

Cellular Component

Where in the cell the gene product is active
  • cell cortex

Molecular Function

What the gene product does at the molecular level
  • lipid binding
  • actin monomer binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.