SLC36A3 Gene Summary [Human]
Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport and proton transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SLC36A3 |
| Official Name | solute carrier family 36 member 3 [Source:HGNC Symbol;Acc:HGNC:19659] |
| Ensembl ID | ENSG00000186334 |
| Bio databases IDs | |
| Aliases | solute carrier family 36 member 3 |
| Synonyms | PAT3, solute carrier family 36 member 3, solute carrier family 36 (proton/amino acid symporter), member 3, TRAMD2, tramdorin2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC36A3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Solute carrier families 5 and 6-like; solute binding domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
- diabetes mellitus
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC36A3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- L-alanine transport
- glycine transport
- proline transmembrane transport
Cellular Component
Where in the cell the gene product is active
- vacuolar membrane
Molecular Function
What the gene product does at the molecular level
- hydrogen:amino acid symporter activity
- glycine transmembrane transporter activity
- L-proline transmembrane transporter activity
- L-alanine transmembrane transporter activity