CFAP73 Gene Summary [Human]
Predicted to enable dynein complex binding activity. Predicted to be involved in cilium movement and inner dynein arm assembly. Predicted to be located in axonemal outer doublet and motile cilium. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CFAP73 |
| Official Name | cilia and flagella associated protein 73 [Source:HGNC Symbol;Acc:HGNC:37100] |
| Ensembl ID | ENSG00000186710 |
| Bio databases IDs | |
| Aliases | cilia and flagella associated protein 73 |
| Synonyms | CCDC42B, cilia and flagella associated protein 73, Gm5988, MIA2, RGD1561303 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CFAP73 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- Domain of unknown function (DUF4200)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CFAP73 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
- cilium movement
- inner dynein arm assembly
Cellular Component
Where in the cell the gene product is active
- motile cilium
Molecular Function
What the gene product does at the molecular level
- dynein complex binding