PLEKHG7 Gene Summary [Human]
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Rho protein signal transduction. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PLEKHG7 |
| Official Name | pleckstrin homology and RhoGEF domain containing G7 [Source:HGNC Symbol;Acc:HGNC:33829] |
| Ensembl ID | ENSG00000187510 |
| Bio databases IDs | |
| Aliases | pleckstrin homology and RhoGEF domain containing G7 |
| Synonyms | AC115970.1, C12orf74, Gm49817, LOC102549785, pleckstrin homology and RhoGEF domain containing G7, predicted gene, 49817 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PLEKHG7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RhoGEF
- Domain of unknown function (DUF4675)
- protein binding
- Pleckstrin homology-like domain
- Pleckstrin homology domain
- RhoGEF domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PLEKHG7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Rho protein signal transduction
Molecular Function
What the gene product does at the molecular level
- protein binding
- guanyl-nucleotide exchange factor activity