DHRS4L2 Gene Summary [Human]
This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Details
| Type | Protein Coding |
| Official Symbol | DHRS4L2 |
| Official Name | dehydrogenase/reductase 4 like 2 [Source:HGNC Symbol;Acc:HGNC:19731] |
| Ensembl ID | ENSG00000187630 |
| Bio databases IDs | |
| Aliases | dehydrogenase/reductase 4 like 2, short chain dehydrogenase/reductase family 25C, member 3 |
| Synonyms | dehydrogenase/reductase 4 like 2, SDR25C3 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DHRS4L2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- polyketide synthase keto reductase domain
- KR domain
- short chain dehydrogenase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DHRS4L2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- retinal metabolic process
Cellular Component
Where in the cell the gene product is active
- peroxisome
- extracellular region
Molecular Function
What the gene product does at the molecular level
- carbonyl reductase (NADPH) activity