SPRR2F Gene Summary [Human]

Predicted to be involved in keratinization. Predicted to act upstream of or within response to estradiol. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
SPRR2F
Official Name
small proline rich protein 2F [Source:HGNC Symbol;Acc:HGNC:11266]
Ensembl ID
ENSG00000244094
Bio databases IDs NCBI: 6705 Ensembl: ENSG00000244094
Aliases small proline rich protein 2F
Synonyms small proline rich protein 2F
Species
Human, Homo sapiens

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chronic periodontal disease
regulated by
  • carbonyl cyanide m-chlorophenyl hydrazone
  • PPRC1
  • meclizine
  • SN-38
  • N-acetyl-L-cysteine
  • SERPINB7
  • NRF1
  • vitamin K3
  • U-2 OS cells

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cornified envelope
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SPRR2F gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • keratinocyte differentiation
  • epidermis development
  • keratinization

Cellular Component

Where in the cell the gene product is active
  • cornified envelope
  • cytosol

Gene-Specific Assays for Results You Can Trust

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