RBM14-RBM4 Gene Summary [Human]

This locus represents naturally occurring read-through transcription between the neighboring RBM14 (RNA binding motif protein 14) and RBM4 (RNA binding motif protein 4) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This fusion protein contains RRM and zinc finger domains, and it functions to stimulate transcription in a hormone and receptor-dependent manner. [provided by RefSeq, Nov 2010]

Details

Type
Protein Coding
Official Symbol
RBM14-RBM4
Official Name
RBM14-RBM4 readthrough [Source:HGNC Symbol;Acc:HGNC:38840]
Ensembl ID
ENSG00000248643
Bio databases IDs NCBI: 100526737 Ensembl: ENSG00000248643
Aliases RBM14-RBM4 readthrough
Synonyms COAZ, Gm21992, predicted gene 21992, PSP2, RBM14, RBM14-RBM4 readthrough, SIP
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBM14-RBM4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc knuckle
  • ELAV/HuD family splicing factor
  • zinc finger
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • Occluded RNA-recognition motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • migraines
regulated by
  • N,N,N',N'-tetrakis(2-pyridyl-methyl)ethylenediamine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene-Specific Assays for Results You Can Trust

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