RNA5-8SN5 Gene Summary [Human]
45S ribosomal DNA (rDNA) arrays, or clusters, are present on human chromosomes 13, 14, 15, 21 and 22, designated RNR1 through RNR5, respectively. Each cluster consists of multiple 45S rDNA repeat units that vary in number among individuals and chromosomes, with total diploid copy number estimates ranging from 60 to >800 repeat units in a human genome. The 45S rDNA repeat unit encodes a 45S rRNA precursor, transcribed by RNA polymerase I, which is processed to form the 18S, 5.8S and 28S rRNAs. This gene is a representative copy of the 5.8S ribosomal RNA whose chromosomal location is unknown. [provided by RefSeq, Mar 2017]
Details
| Type | Ribosomal RNA |
| Official Symbol | RNA5-8SN5 |
| Official Name | RNA, 5.8S ribosomal N5 [Source:HGNC Symbol;Acc:HGNC:53533] |
| Ensembl ID | ENSG00000274917 |
| Bio databases IDs | |
| Aliases | RNA, 5.8S ribosomal N5 |
| Synonyms | 5.8S, LOC124908526, RN5-8S1, RNA5-8S5, RNA, 5.8S ribosomal N5 |
| Species | Human, Homo sapiens |
Pathways
Biological processes and signaling networks where the RNA5-8SN5 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RNA5-8SN5 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- ribosome
Molecular Function
What the gene product does at the molecular level
- structural constituent of ribosome