Trpm5

Enables calcium-activated cation channel activity; potassium channel activity; and sodium channel activity. Involved in monoatomic ion transmembrane transport and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in dendrite; membrane; and neuronal cell body. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including ganglia; genitourinary system; gut; hemolymphoid system gland; and liver and biliary system. Orthologous to human TRPM5 (transient receptor potential cation channel subfamily M member 5). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trpm5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Trpm5 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Trpm5 gene, providing context for its role in the cell.