Trim52 Gene Summary [Mouse]
Predicted to enable transcription coactivator activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of NF-kappaB transcription factor activity; and positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Orthologous to human TRIM52 (tripartite motif containing 52). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trim52 |
| Official Name | tripartite motif-containing 52 [Source:MGI Symbol;Acc:MGI:3045276] |
| Ensembl ID | ENSMUSG00000022113 |
| Bio databases IDs | |
| Aliases | tripartite motif-containing 52 |
| Synonyms | 4921513B05Rik, RGD1565615, tripartite motif-containing 52 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trim52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription co-activator
- RING-type zinc-finger
- zinc finger of C3HC4-type, RING
- ubiquitin protein ligase activity
- enzyme
- Zinc finger, C3HC4 type (RING finger)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol