Ndufb4 Gene Summary [Mouse]

Predicted to be involved in mitochondrial respiratory chain complex I assembly and response to oxidative stress. Located in mitochondrion. Part of respiratory chain complex I. Is active in mitochondrial inner membrane. Is expressed in cerebral cortex; cranium; and early conceptus. Orthologous to human NDUFB4 (NADH:ubiquinone oxidoreductase subunit B4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ndufb4
Official Name
NADH:ubiquinone oxidoreductase subunit B4 [Source:MGI Symbol;Acc:MGI:1915444]
Ensembl ID
ENSMUSG00000022820
Bio databases IDs NCBI: 68194 NCBI: 100041273 NCBI: 100042503 Ensembl: ENSMUSG00000022820
Aliases NADH:ubiquinone oxidoreductase subunit B4
Synonyms Gm3244, Gm3873, NADH:ubiquinone oxidoreductase subunit B4B, NADH:ubiquinone oxidoreductase subunit B4C, NADH:ubiquinone oxidoreductase subunit B4-like 1, NADH:ubiquinone oxidoreductase subunit B4 like 3, NADH:ubiquinone oxidoreductase subunit B4 like 4, Ndufb4b, Ndufb4c, Ndufb4l1, Ndufb4l1-ps1, Ndufb4l3, Ndufb4l4, RGD1560088, RGD1560413
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ndufb4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)

Pathways

Biological processes and signaling networks where the Ndufb4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial inner membrane
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

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