Crisp4 Gene Summary [Mouse]
Enables calcium channel regulator activity. Acts upstream of or within binding activity of sperm to zona pellucida and regulation of acrosome reaction. Predicted to be active in extracellular space. Orthologous to human CRISP1 (cysteine rich secretory protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Crisp4 |
| Official Name | cysteine-rich secretory protein 4 [Source:MGI Symbol;Acc:MGI:1925331] |
| Ensembl ID | ENSMUSG00000025774 |
| Bio databases IDs | |
| Aliases | cysteine-rich secretory protein 4 |
| Synonyms | 9230112K08Rik, cysteine-rich secretory protein 4 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Crisp4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Crisp
- SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains
- CAP
- calcium channel regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
- fertilization by
- binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown