Serpinb8 Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in epithelial cell-cell adhesion and negative regulation of endopeptidase activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in peeling skin syndrome 5. Orthologous to human SERPINB8 (serpin family B member 8). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Serpinb8 |
| Official Name | serine (or cysteine) peptidase inhibitor, clade B, member 8 [Source:MGI Symbol;Acc:MGI:894657] |
| Ensembl ID | ENSMUSG00000026315 |
| Bio databases IDs | |
| Aliases | serine (or cysteine) peptidase inhibitor, clade B, member 8 |
| Synonyms | CAP-2, NK10, ovalbumin, serine (or cysteine) peptidase inhibitor, clade B, member 8, Spi8 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Serpinb8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SERine Proteinase INhibitors (serpin) family
- serine protease inhibitor activity
- Serpin (serine protease inhibitor)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol