Atp6v1g3 Gene Summary [Mouse]
Enables proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in synaptic vesicle lumen acidification. Predicted to act upstream of or within proton transmembrane transport. Located in cytosol and plasma membrane. Is expressed in embryo; forelimb bud; metanephros; and olfactory epithelium. Orthologous to human ATP6V1G3 (ATPase H+ transporting V1 subunit G3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atp6v1g3 |
| Official Name | ATPase, H+ transporting, lysosomal V1 subunit G3 [Source:MGI Symbol;Acc:MGI:2450548] |
| Ensembl ID | ENSMUSG00000026394 |
| Bio databases IDs | |
| Aliases | ATPase, H+ transporting, lysosomal V1 subunit G3 |
| Synonyms | ATP6G3, Atp6v1g3 (predicted), ATPase, H+ transporting, lysosomal V1 subunit G3, ATPase H+ transporting V1 subunit G3, Vma10 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp6v1g3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Vacuolar (H+)-ATPase G subunit
- ATPase binding
- vacuolar ATP synthase, subunit G
- H+-transporting two-sector ATPase
- hydrogen-transporting ATPase activity, rotational mechanism
- protein binding
- transporter
Pathways
Biological processes and signaling networks where the Atp6v1g3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- cellular membrane
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp6v1g3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- vacuolar proton-transporting V-type ATPase, V1 domain
- cytosol
- synaptic vesicle membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- proton-transporting ATPase activity, rotational mechanism
- ATPase binding