Ermap Gene Summary [Mouse]
Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Located in cytoplasmic vesicle. Is expressed in bone marrow; embryo; liver; and spleen. Orthologous to human ERMAP (erythroblast membrane associated protein (Scianna blood group)). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ermap |
| Official Name | erythroblast membrane-associated protein [Source:MGI Symbol;Acc:MGI:1349816] |
| Ensembl ID | ENSMUSG00000028644 |
| Bio databases IDs | |
| Aliases | erythroblast membrane-associated protein |
| Synonyms | BTN5, erythroblast membrane-associated protein, erythroblast membrane associated protein (Scianna blood group), PRO2801, RD, SC |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ermap often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SPRY domain
- Immunoglobulin V-Type
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- associated with SPRY domains
- SPRY-associated domain
- Immunoglobulin V-set domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- Golgi Apparatus
- cytosol
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ermap gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cytokine production
- T cell receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- external side of plasma membrane
- cytosol
- Golgi apparatus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- receptor binding