N4bp2l2 Gene Summary [Mouse]
Enables transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within blastocyst development. Located in nucleus. Orthologous to human N4BP2L2 (NEDD4 binding protein 2 like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | N4bp2l2 |
| Official Name | NEDD4 binding protein 2-like 2 [Source:MGI Symbol;Acc:MGI:2687207] |
| Ensembl ID | ENSMUSG00000029655 |
| Bio databases IDs | |
| Aliases | NEDD4 binding protein 2-like 2 |
| Synonyms | 2700092H06Rik, Gm38758, NEDD4 binding protein 2-like 2, zag1 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse N4bp2l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- transcription co-repressor
- enzyme binding
- protein binding
- AAA domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulates
- DNA promoter
- DNA endogenous promoter
- RNA polymerase II
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm