2210010C04Rik Gene Summary [Mouse]
Enables serine-type endopeptidase activity. Acts upstream of or within zymogen activation. Predicted to be active in extracellular space. Is expressed in ductus deferens; gallbladder; pancreas; pancreas tip epithelium; and testis. Used to study pancreatitis. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | 2210010C04Rik |
| Official Name | RIKEN cDNA 2210010C04 gene [Source:MGI Symbol;Acc:MGI:1914623] |
| Ensembl ID | ENSMUSG00000029882 |
| Bio databases IDs | |
| Aliases | RIKEN cDNA 2210010C04 gene |
| Synonyms | 2210010C04Rik, protease, serine, 3B, Prss3, serine protease 3B, T7, T7 trypsinogen, Try3, Trypsinogen |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse 2210010c04rik often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- enteropeptidase cleavage site
- peptidase
Pathways
Biological processes and signaling networks where the 2210010c04rik gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pancreatitis
- chronic pancreatitis
phenotypes
- abnormal retinal vasculature morphology
- decreased circulating alanine transaminase level
- abnormal pancreas morphology
- acute pancreas inflammation
- chronic pancreas inflammation
- decreased body size
- decreased circulating amylase level
- decreased pancreas weight
- decreased pancreatic acinar cell number
- enlarged pancreatic islets
- increased pancreas weight
- pancreas atrophy
- premature death
- small pancreas
role in cell
- apoptosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space