Kctd13 Gene Summary [Mouse]
Enables identical protein binding activity. Involved in negative regulation of Rho protein signal transduction and positive regulation of synaptic transmission. Predicted to be located in nuclear body. Predicted to be part of Cul3-RING ubiquitin ligase complex. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human KCTD13 (potassium channel tetramerization domain containing 13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kctd13 |
| Official Name | potassium channel tetramerisation domain containing 13 [Source:MGI Symbol;Acc:MGI:1923739] |
| Ensembl ID | ENSMUSG00000030685 |
| Bio databases IDs | |
| Aliases | potassium channel tetramerisation domain containing 13 |
| Synonyms | 1500003N18RIK, AV259508, BACURD1, CTB52, D5Mgi41, FKSG86, hBACURD1, PDIP1, PDIP1alpha, POLDIP1, polymerase δ-interacting protein 1, potassium channel tetramerisation domain containing 13, potassium channel tetramerization domain containing 13 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kctd13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- ubiquitin-protein transferase activity
- enzyme binding
- protein domain specific binding
- protein binding
- identical protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- nuclear bodies
- DNA replication foci
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kctd13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
- negative regulation of Rho protein signal transduction
- neural precursor cell proliferation
- positive regulation of synaptic transmission
- protein homooligomerization
- stress fiber assembly
- cell migration
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nuclear body
- cytosol
- Cul3-RING ubiquitin ligase complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ubiquitin-protein ligase activity
- identical protein binding
- protein binding
- small GTPase binding