Rbm3 Gene Summary [Mouse]
Enables ribosomal large subunit binding activity. Involved in regulation of translation. Acts upstream of or within miRNA processing; response to cold; and translation. Predicted to be located in cytoplasm; dendrite; and nucleoplasm. Predicted to be part of large ribosomal subunit and spliceosomal complex. Is expressed in several structures, including central nervous system; ovary; and sensory organ. Orthologous to human RBM3 (RNA binding motif protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Rbm3 |
| Official Name | RNA binding motif (RNP1, RRM) protein 3 [Source:MGI Symbol;Acc:MGI:1099460] |
| Ensembl ID | ENSMUSG00000031167 |
| Bio databases IDs | |
| Aliases | RNA binding motif (RNP1, RRM) protein 3 |
| Synonyms | Gm15453, RNA binding motif (RNP1, RRM) protein 3 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rbm3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
phenotypes
- hypoactivity
- increased thigmotaxis
- abnormal cell cycle
- abnormal developmental patterning
- absent somites
- decreased fibroblast proliferation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm