Nlrp4f Gene Summary [Mouse]
Predicted to enable molecular adaptor activity. Involved in several processes, including actin filament organization; in utero embryonic development; and positive regulation of embryonic development. Located in cell cortex. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; liver; and muscle tissue. Orthologous to human NLRP4 (NLR family pyrin domain containing 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Nlrp4f |
| Official Name | NLR family, pyrin domain containing 4F [Source:MGI Symbol;Acc:MGI:2145528] |
| Ensembl ID | ENSMUSG00000032999 |
| Bio databases IDs | |
| Aliases | NLR family, pyrin domain containing 4F |
| Synonyms | C330026N02Rik, LOC683736, Nalp4f, Nalp-kappa, Nalp-κ, NLR family, pyrin domain containing 4F |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nlrp4f often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NLRC4 helical domain HD2
- PAAD/DAPIN/Pyrin domain
- NOD2 winged helix domain
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat, ribonuclease inhibitor type
- Leucine rich repeat
- protein binding
- NACHT domain
- Death Domain Superfamily of protein-protein interaction domains
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
phenotypes
- abnormal oocyte morphology
- decreased litter size
- maternal effect
- reduced female fertility
role in cell
- growth
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell cortex