Nlrp4f Gene Summary [Mouse]
Predicted to enable molecular adaptor activity. Involved in several processes, including actin filament organization; in utero embryonic development; and positive regulation of embryonic development. Located in cell cortex. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; liver; and muscle tissue. Orthologous to human NLRP4 (NLR family pyrin domain containing 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Nlrp4f |
| Official Name | NLR family, pyrin domain containing 4F [Source:MGI Symbol;Acc:MGI:2145528] |
| Ensembl ID | ENSMUSG00000032999 |
| Bio databases IDs | |
| Aliases | NLR family, pyrin domain containing 4F |
| Synonyms | C330026N02Rik, LOC683736, Nalp4f, Nalp-kappa, Nalp-κ, NLR family, pyrin domain containing 4F |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nlrp4f often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NLRC4 helical domain HD2
- PAAD/DAPIN/Pyrin domain
- NOD2 winged helix domain
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat, ribonuclease inhibitor type
- Leucine rich repeat
- protein binding
- NACHT domain
- Death Domain Superfamily of protein-protein interaction domains
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
- growth
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell cortex