Zmynd15 Gene Summary [Mouse]
Enables histone deacetylase binding activity. Acts upstream of or within negative regulation of DNA-templated transcription and spermatid development. Located in cytoplasm and male germ cell nucleus. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in spermatogenic failure 14. Orthologous to human ZMYND15 (zinc finger MYND-type containing 15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zmynd15 |
| Official Name | zinc finger, MYND-type containing 15 [Source:MGI Symbol;Acc:MGI:3603821] |
| Ensembl ID | ENSMUSG00000040829 |
| Bio databases IDs | |
| Aliases | zinc finger, MYND-type containing 15 |
| Synonyms | SPGF14, zinc finger MYND-type containing 15, zinc finger, MYND-type containing 15 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zmynd15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MYND finger
- MSS51 C-terminal domain
- histone deacetylase binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zmynd15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- spermatid development
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- male germ cell nucleus
Molecular Function
What the gene product does at the molecular level
- histone deacetylase binding
- metal ion binding