Dcaf12l1 Gene Summary [Mouse]
Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Is expressed in extraembryonic ectoderm; follicle cell of primordial follicle; and ovary. Orthologous to human DCAF12L1 (DDB1 and CUL4 associated factor 12 like 1) and DCAF12L2 (DDB1 and CUL4 associated factor 12 like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dcaf12l1 |
| Official Name | DDB1 and CUL4 associated factor 12-like 1 [Source:MGI Symbol;Acc:MGI:2444462] |
| Ensembl ID | ENSMUSG00000045284 |
| Bio databases IDs | |
| Aliases | DDB1 and CUL4 associated factor 12-like 1 |
| Synonyms | 9330180J20, A230038L21Rik, Dcaf12, DDB1 and CUL4 associated factor 12-like 1, Decaf12l1, RGD1563873, Wdr40b |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dcaf12l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm