Hsf3 Gene Summary [Mouse]
Enables chromatin DNA binding activity and sequence-specific DNA binding activity. Involved in cellular response to heat and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in eye; genital tubercle; genitourinary system; heart; and limb. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hsf3 |
| Official Name | heat shock transcription factor 3 [Source:MGI Symbol;Acc:MGI:3045337] |
| Ensembl ID | ENSMUSG00000045802 |
| Bio databases IDs | |
| Aliases | heat shock transcription factor 3 |
| Synonyms | B230358A15Rik, heat shock transcription factor 3, HSTF 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hsf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- HSF-type DNA-binding
- DNA binding domain
- HR domain
- chromatin binding
- sequence-specific DNA binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus