Exd1 Gene Summary [Mouse]
Predicted to enable RNA binding activity and protein homodimerization activity. Involved in piRNA processing. Part of PET complex. Is expressed in testis. Orthologous to human EXD1 (exonuclease 3'-5' domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Exd1 |
| Official Name | exonuclease 3'-5' domain containing 1 [Source:MGI Symbol;Acc:MGI:3045306] |
| Ensembl ID | ENSMUSG00000048647 |
| Bio databases IDs | |
| Aliases | exonuclease 3'-5' domain containing 1 |
| Synonyms | 4932702D22Rik, EXDL1, exonuclease 3'-5' domain containing 1, mExd1, RGD1561009 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Exd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily
- protein homodimerization
- protein binding
- RNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cytoplasmic ribonucleoprotein granule
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Exd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- meiotic cell cycle
- gene silencing by RNA
- piRNA metabolic process
Cellular Component
Where in the cell the gene product is active
- P granule
Molecular Function
What the gene product does at the molecular level
- 3'-5' exonuclease activity
- protein homodimerization activity
- RNA binding
- protein binding