Prdx6b Gene Summary [Mouse]

This intronless gene is similar to the multi-exon peroxiredoxin 6 gene located on chromosome 1. It is transcribed and the ORF is intact compared to that of the peroxiredoxin 6 gene. This gene could be considered a transcribed pseudogene based on a failure to detect the protein in vivo in PMID:14644414. However, NCBI is representing the protein due to mass spectrometry data in PMID:18614015, which detected at least one peptide that is specific for this protein. [provided by RefSeq, Mar 2011]

Details

Type
Protein Coding
Official Symbol
Prdx6b
Official Name
peroxiredoxin 6B [Source:MGI Symbol;Acc:MGI:1336888]
Ensembl ID
ENSMUSG00000050114
Bio databases IDs NCBI: 320769 Ensembl: ENSMUSG00000050114
Aliases peroxiredoxin 6B
Synonyms 1-cysPrx-P1, 4930414C22Rik, Aop2-rs1, peroxiredoxin 6B, Prdx5-rs1, Prdx6-ps1, Prdx6-rs1, Prdx6-rs1-ps
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prdx6b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ubiquitin protein ligase binding
  • C-terminal domain of 1-Cys peroxiredoxin
  • Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
  • calcium-independent phospholipase A2
  • 1-acylglycerophosphocholine O-acyltransferase
  • AhpC/TSA family
  • enzyme
  • glutathione peroxidase
  • identical protein binding
  • phospholipase A2

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • perinuclear region
  • Nucleus

Gene-Specific Assays for Results You Can Trust

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