Ctf2 Gene Summary [Mouse]
Enables ciliary neurotrophic factor receptor binding activity and leukemia inhibitory factor receptor binding activity. Acts upstream of or within positive regulation of neuroblast proliferation. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Is expressed in several structures, including central nervous system; lung; metanephros; neural retinal epithelium; and skin. Orthologous to human CTF2P (cardiotrophin 2, pseudogene). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ctf2 |
| Official Name | cardiotrophin 2 [Source:MGI Symbol;Acc:MGI:2684607] |
| Ensembl ID | ENSMUSG00000060034 |
| Bio databases IDs | |
| Aliases | cardiotrophin 2 |
| Synonyms | cardiotrophin 2, Ctf2p, Gm494, Neuropoietin, NP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ctf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- leukemia inhibitory factor receptor binding
- ciliary neurotrophic factor receptor binding
- protein binding
- cytokine
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space