Nlrp9b Gene Summary [Mouse]
Predicted to enable ATP binding activity. Involved in defense response to other organism; positive regulation of interleukin-18 production; and pyroptotic inflammatory response. Acts upstream of or within blastocyst development. Predicted to be part of canonical inflammasome complex. Predicted to be active in cytoplasm. Is expressed in early conceptus; intestine; ovary; and testis. Orthologous to human NLRP9 (NLR family pyrin domain containing 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nlrp9b |
| Official Name | NLR family, pyrin domain containing 9B [Source:MGI Symbol;Acc:MGI:2675377] |
| Ensembl ID | ENSMUSG00000060508 |
| Bio databases IDs | |
| Aliases | NLR family, pyrin domain containing 9B |
| Synonyms | Nalp9b, Nalp-delta, Nalp-δ, NLR family, pyrin domain containing 9B, Nlrp9 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nlrp9b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NLRC4 helical domain HD2
- PAAD/DAPIN/Pyrin domain
- NOD2 winged helix domain
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat, ribonuclease inhibitor type
- protein binding
- NACHT domain
- Death Domain Superfamily of protein-protein interaction domains
- P-loop containing Nucleoside Triphosphate Hydrolases
Pathways
Biological processes and signaling networks where the Nlrp9b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown