Adam1b Gene Summary [Mouse]
Predicted to enable metalloendopeptidase activity. Predicted to be involved in binding activity of sperm to zona pellucida; male gonad development; and proteolysis. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane and sperm head plasma membrane. Orthologous to human ADAM1B (ADAM metallopeptidase domain 1B (pseudogene)). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adam1b |
| Official Name | a disintegrin and metallopeptidase domain 1b [Source:MGI Symbol;Acc:MGI:2429506] |
| Ensembl ID | ENSMUSG00000062438 |
| Bio databases IDs | |
| Aliases | a disintegrin and metallopeptidase domain 1b |
| Synonyms | Adam1, a disintegrin and metallopeptidase domain 1b, Ftna, LOC100047841 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adam1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Myxococcus cysteine-rich repeat
- Reprolysin family propeptide
- ZnMc
- ADAM cysteine-rich
- Metallo-peptidase family M12B Reprolysin-like
- Disintegrin
- Reprolysin (M12B) family zinc metalloprotease
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane