Btnl1 Gene Summary [Mouse]

Predicted to enable signaling receptor binding activity. Involved in extrathymic T cell selection. Located in cell surface. Is expressed in ductus deferens; epididymis; ileum; prostate gland; and testis. [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Btnl1
Official Name
butyrophilin-like 1 [Source:MGI Symbol;Acc:MGI:1932027]
Ensembl ID
ENSMUSG00000062638
Bio databases IDs NCBI: 100038862 Ensembl: ENSMUSG00000062638
Aliases butyrophilin-like 1
Synonyms Btnl3, butyrophilin-like 1, butyrophilin-like 3, Gm316, Gm33
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Btnl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SPRY domain
  • Immunoglobulin V-Type
  • immunoglobulin domain
  • Immunoglobulin like
  • Immunoglobulin I-set domain
  • Immunoglobulin V-set domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
phenotypes
  • abnormal CD8 positive alpha-beta intraepithelial T cell morphology
  • decreased gamma-delta intraepithelial T cell number

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • cellular membrane

Gene-Specific Assays for Results You Can Trust

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