Mrgprx2 Gene Summary [Mouse]
Enables mast cell secretagogue receptor activity. Involved in mast cell activation. Predicted to be active in plasma membrane. Orthologous to several human genes including MRGPRX2 (MAS related GPR family member X2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrgprx2 |
| Official Name | MAS-related GPR, member X2 [Source:MGI Symbol;Acc:MGI:3588270] |
| Ensembl ID | ENSMUSG00000074109 |
| Bio databases IDs | |
| Aliases | MAS-related GPR, member X2 |
| Synonyms | G370024M05Rik, MAS related GPR family member X2, MAS-related GPR, member B1, MAS-related GPR, member X2, Mgrg6, MrgB1, MrgB10, Mrgprb1, Mrgprb10, Mrgprx2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrgprx2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- neuropeptide binding
- 7 transmembrane receptor (rhodopsin family)
- seven-transmembrane G protein-coupled receptor superfamily
- transmembrane receptor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- beta-estradiol
- 10E,12Z-octadecadienoic acid
role in cell
- activation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane