F8a Gene Summary [Mouse]
Predicted to be involved in negative regulation of proteasomal protein catabolic process and vesicle cytoskeletal trafficking. Located in cytoplasm and nuclear body. Is expressed in several structures, including gut; liver lobe; lower urinary tract; pharyngo-tympanic tube; and submandibular gland primordium. Orthologous to human F8A1 (coagulation factor VIII associated 1); F8A2 (coagulation factor VIII associated 2); and F8A3 (coagulation factor VIII associated 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | F8a |
| Official Name | factor 8-associated gene A [Source:MGI Symbol;Acc:MGI:95474] |
| Ensembl ID | ENSMUSG00000078317 |
| Bio databases IDs | |
| Aliases | factor 8-associated gene A |
| Synonyms | coagulation factor VIII-associated 1, DXUcsf1, F8a1, factor 8-associated gene A, HAP40, RGD1566014 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse F8a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cell cortex
- nuclear bodies
- early endosomes