Calhm1

Enables voltage-gated calcium channel activity. Involved in ATP export; protein heterooligomerization; and sensory perception of taste. Located in basolateral plasma membrane and plasma membrane raft. Is expressed in forebrain; gut; and male reproductive gland or organ. Orthologous to human CALHM1 (calcium homeostasis modulator 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Calhm1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Calhm1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.