Slco1a6 Gene Summary [Mouse]

Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Acts upstream of or within several processes, including bile acid metabolic process; cholesterol homeostasis; and triglyceride homeostasis. Predicted to be located in basal plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in brain ventricle and choroid plexus; metanephros; and telencephalon ventricular layer. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slco1a6
Official Name
solute carrier organic anion transporter family, member 1a6 [Source:MGI Symbol;Acc:MGI:1351906]
Ensembl ID
ENSMUSG00000079262
Bio databases IDs NCBI: 28254 Ensembl: ENSMUSG00000079262
Aliases solute carrier organic anion transporter family, member 1a6
Synonyms 4930422F19Rik, Oatp-5, Slc21a13, solute carrier organic anion transporter family, member 1a6
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slco1a6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Organic Anion Transporter Polypeptide (OATP) family
  • Major Facilitator Superfamily
  • sodium-independent organic anion transporter
  • organic anion transporter
  • KAZAL_FS
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • streptozotocin-induced diabetic nephropathy
regulated by
  • MAFA
  • FECH
  • HNF1A
  • fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
regulates
  • triacylglycerol
  • heme
  • bile acid
  • xenobiotic
  • cholesterol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • basal membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.