Slco1a6 Gene Summary [Rat]

Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Involved in liver regeneration. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slco1a6
Official Name
solute carrier organic anion transporter family, member 1a6 [Source:RGD Symbol;Acc:69304]
Ensembl ID
ENSRNOG00000030894
Bio databases IDs NCBI: 84608 Ensembl: ENSRNOG00000030894
Aliases solute carrier organic anion transporter family, member 1a6
Synonyms 4930422F19Rik, Oatp-5, Slc21a13, solute carrier organic anion transporter family, member 1a6
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slco1a6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Organic Anion Transporter Polypeptide (OATP) family
  • Major Facilitator Superfamily
  • sodium-independent organic anion transporter
  • organic anion transporter
  • KAZAL_FS
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • streptozotocin-induced diabetic nephropathy
regulated by
  • MAFA
  • FECH
  • HNF1A
  • fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
regulates
  • triacylglycerol
  • heme
  • bile acid
  • xenobiotic
  • cholesterol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • basal membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.